Anti-Aging and Age Management in Denver
Aging is a natural process, but the way we age can vary considerably from person to person. Genetics, lifestyle, hormonal changes, metabolism, and overall health all influence how we feel and function as we get older.
At Bionuu Functional Medicine Denver, we offer a physician-led approach to age management that focuses on maintaining health, physical and mental function, and quality of life as we age. Our approach combines conventional medical knowledge with functional and integrative medicine. Depending on your individual needs, your care plan may include hormone therapy, NAD+, peptides, Rapamycin, intravenous nutrient therapy, ozone therapy, and other selected treatments. Located in Centennial, Colorado, our clinic serves patients throughout the greater Denver area.

What Is Age Management Medicine?
Age management, sometimes called anti-aging medicine, is a proactive approach to health that focuses on the physical and biological changes associated with aging.
As we grow older, changes occur in hormone production, metabolism, muscle mass, body composition, cellular function, and many other processes. These changes do not affect everyone in the same way or at the same rate.
Age management medicine looks at these changes individually, rather than assuming that every symptom or decline in function is simply an unavoidable part of getting older.
The goal is not to stop aging, but to identify factors that may affect health and function and determine whether they can be addressed.
At Bionuu, age management is not a standardized treatment package. It begins with a comprehensive medical evaluation, followed by laboratory testing when appropriate.
Based on the findings, Dr. Sorina Simion-Rodgers develops an individualized plan that may include medical treatment, nutritional recommendations, lifestyle changes, and selected complementary therapies.
Age management is part of our broader Functional and Integrative Medicine approach.
Who May Benefit From Age Management?
People consider age management for many different reasons.
Some begin to notice changes in energy, strength, sleep, memory, or body composition. Others feel generally well but want to take a more proactive approach to maintaining their health.
Age management may be of interest to people experiencing:
- Reduced energy or stamina
- Changes in muscle mass or strength
- Increased body fat or changes in body composition
- Slower recovery after physical activity
- Changes in memory, concentration, or mental clarity
- Sleep disturbances
- Hormonal changes
- Metabolic concerns
- Reduced physical resilience
- A desire to maintain long-term health and function
Areas We Focus On
Energy and Vitality
Fatigue and reduced stamina can be influenced by many factors, including sleep, nutrition, hormonal changes, metabolic health, and underlying medical conditions. We evaluate possible contributing factors before recommending treatment.
Muscle Mass, Strength, and Body Composition
Changes in muscle mass, fat distribution, and physical strength are common with aging. Our approach considers hormonal and metabolic factors alongside nutrition, physical activity, and other aspects of health that influence body composition.
Memory, Concentration, and Mental Clarity
Changes in memory, focus, and mental clarity may be associated with sleep disturbances, stress, hormonal changes, nutritional deficiencies, medications, chronic infection and inflammation or other medical conditions. We consider these possibilities as part of a broader evaluation.
Recovery and Physical Resilience
Some people notice that they recover more slowly from exercise, physical exertion, or illness as they get older. We assess factors that may influence recovery and discuss appropriate approaches to supporting physical function.
Sleep and Stress
Sleep, hormonal regulation, metabolism, and the body's response to stress are closely connected. Addressing sleep and stress-related concerns may be an important part of an individualized age management plan.
Cellular Health and Energy Production
Cellular energy production is essential for normal body function and changes with aging. Some therapies used in age management, including NAD+, are being investigated for their potential effects on cellular metabolism and related biological processes. The clinical benefits of these approaches continue to be studied.
Long-Term Health
Age management also emphasizes prevention and maintaining function over time. Rather than focusing only on current symptoms, we consider factors that may influence future health and quality of life.
Age Management Therapies Available at Bionuu
The therapies included in an age management plan depend on your medical evaluation, laboratory findings, health concerns, and goals. Not every patient needs or qualifies for these treatments.
Hormones influence many aspects of health, including metabolism, sleep, mood, energy, reproductive function, and body composition. Hormonal changes may occur naturally with age, but symptoms that appear to be hormone-related can also have other causes.
At Bionuu, hormone therapy begins with a review of symptoms, medical history, and appropriate laboratory testing. When treatment is indicated, we develop an individualized plan that may include bioidentical hormones. Hormone therapy is not automatically recommended based on age alone.
Learn moreNicotinamide adenine dinucleotide (NAD+) is a coenzyme found in living cells. It participates in numerous biological processes, including cellular energy production and metabolic regulation. NAD+ levels and metabolism have become areas of interest in aging research.
At Bionuu, intravenous NAD+ therapy may be considered as part of an individualized age management plan. Although NAD+ has important biological functions, research is still evaluating whether intravenous supplementation produces meaningful long-term benefits for healthy aging.
Peptides are short chains of amino acids that perform many functions in the body, including acting as signaling molecules. Different peptides have different biological activities and are being studied for their potential roles in metabolism, tissue repair, sleep, body composition, and other processes.
At Bionuu, peptide therapy may be considered when appropriate following a medical evaluation. The available research, potential benefits, limitations, and possible adverse effects depend on the specific peptide. There is no single peptide treatment suitable for everyone.
Learn moreRapamycin is a prescription medication that has attracted growing interest in age management because of its effects on the mTOR pathway, which plays an important role in cellular growth, metabolism, autophagy, and aging.
Research in animal models has demonstrated that rapamycin can extend lifespan and influence several biological processes associated with aging. Human studies are exploring its potential effects on immune function, age-related conditions, and longevity, although its ability to extend human lifespan has not been established.
At Bionuu, rapamycin therapy may be considered as part of an individualized age management plan following a comprehensive medical evaluation. Treatment decisions take into account the patient's medical history, potential benefits, side effects, and the need for appropriate laboratory monitoring.
Ozone therapy is one of the complementary approaches offered at our clinic. Medical ozone has been investigated for its effects on oxidative signaling, inflammatory pathways, and other biological processes.
Some practitioners incorporate ozone therapy into broader wellness and age management programs. However, its clinical benefits for slowing biological aging or improving longevity have not been established. At Bionuu, ozone therapy is considered individually and administered under physician supervision.
Learn moreIntravenous nutrient therapy involves administering selected vitamins, minerals, amino acids, and other compounds directly into the bloodstream. IV therapy may be considered for specific nutritional or medical needs or as part of an individualized integrative care plan.
The formulations are selected according to the patient's medical history, clinical findings, and treatment goals. All IV therapies are administered by trained nursing staff under physician supervision.
Learn moreSome prescription medications are being studied for their potential effects on metabolic health, cellular function, and biological processes associated with aging. In certain circumstances, a physician may consider prescribing a medication for a purpose other than its originally approved indication. This is known as off-label prescribing.
The decision depends on the individual patient's medical history, clinical findings, available research, and potential risks and benefits. Not all medications being investigated for age management have demonstrated clinical benefits in humans.
How We Develop Your Age Management Plan
At Bionuu, we believe that age management should begin with understanding your health rather than choosing treatments from a predetermined list.
Comprehensive Medical History
We review your past and current medical conditions, family history, previous treatments, medications, and supplements. This information helps identify factors that may influence your health and the suitability of different therapies.
Discussion of Symptoms and Goals
We take time to understand how you feel, what changes you have noticed, and what you hope to accomplish. Your goals may involve improving energy, maintaining strength, addressing hormonal concerns, supporting metabolic health, or maintaining physical and mental function.
Clinical Evaluation
Dr. Simion-Rodgers evaluates your medical history and current concerns to determine which areas require further investigation.
Laboratory Testing
When appropriate, we recommend laboratory testing to assess relevant aspects of health. Depending on your circumstances, this may include:
Testing is individualized. We do not assume that every patient needs the same laboratory panels.
Personalized Treatment Plan
After reviewing your medical information and test results, we develop a written plan outlining recommendations and priorities. Your plan may include conventional medical treatment, nutritional and lifestyle changes, supplements, and selected age management therapies. Rather than introducing many treatments at once, we generally focus on a few priorities and make adjustments as needed.
Ongoing Monitoring
Age management is an ongoing process. Follow-up visits allow us to review your response, evaluate laboratory results, and adjust recommendations. The frequency of visits and testing depends on your individual circumstances and the treatments being used.
What to Expect During Treatment
Your age management program begins with a comprehensive consultation and medical evaluation. If treatment is recommended, we explain the proposed approach, what it involves, and any relevant considerations.
Depending on your plan, treatment may include office-based procedures, intravenous infusions, hormone management, peptide therapy, or prescribed medications. Some treatments require visits to the clinic, while others may be administered at home when appropriate.
Follow-up appointments are usually more frequent during the initial stages of care and become less frequent as your condition stabilizes. We continue to evaluate your response and make changes when necessary.
Safety and Individual Considerations
Age management treatments should be selected carefully, with attention to each patient's medical history and individual risk factors.
Certain therapies may not be appropriate for people with particular medical conditions or risk factors, including some cancers, cardiovascular conditions, clotting disorders, pregnancy, or breastfeeding. Medications and supplements can also interact with one another.
Before recommending treatment, we review your current medications, supplements, medical conditions, and relevant laboratory findings.
Some age management therapies have been studied extensively, while others have limited human clinical evidence. The potential benefits and risks vary depending on the treatment. We discuss these considerations so patients can make informed decisions. Ongoing clinical assessment and laboratory monitoring are used when appropriate.
Why Choose Bionuu Functional Medicine Denver?
Physician-Led Care
Your care is directed by Dr. Sorina Simion-Rodgers, MD, a physician with more than 20 years of clinical experience and additional training in functional and integrative medicine.
Individualized Evaluation
We do not believe that everyone needs the same hormones, supplements, or age management treatments. Recommendations are based on your medical history, clinical findings, laboratory results, and personal goals.
Conventional and Complementary Approaches
We consider both conventional medical treatments and complementary therapies when developing your care plan. Our goal is to identify approaches that may be appropriate for your individual circumstances.
Multiple Services in One Location
Our clinic offers medical consultations, laboratory testing, hormone management, IV nutrient therapy, NAD+, peptides, ozone therapy, and other complementary services. This allows different aspects of your care to be coordinated within one clinic.
Convenient Denver-Area Location
Bionuu is located in Centennial, Colorado, serving Denver, Highlands Ranch, Littleton, Lone Tree, Greenwood Village, Parker, and surrounding communities.
Dr. Sorina Simion-Rodgers, MD

Dr. Simion-Rodgers has more than 20 years of clinical experience, with a background in Family Medicine and Psychiatry. Her additional education and training include hormonal health, functional and integrative medicine, intravenous medicine, ozone therapy, and emerging approaches to health and wellness. She has also completed training in the Metabolic Approach to Cancer through the Metabolic Terrain Institute of Health.
Her approach emphasizes understanding the individual patient, considering the relationships between different body systems, and developing care plans based on medical history, clinical evaluation, and appropriate testing.
Read More About Dr. Simion-RodgersRelated Services
Hormone Therapy
Individualized thyroid, adrenal, and reproductive hormone management.
Learn morePeptide Therapy
Selected peptides considered as part of a broader care plan.
Learn moreIV Nutrient Therapy
Physician-guided intravenous nutrient and NAD+ therapies.
Learn moreOzone Therapy
Physician-supervised medical ozone treatments.
Learn moreWeber Laser Therapy
Intravenous and targeted light therapies.
Learn moreFunctional and Integrative Medicine
Comprehensive, whole-person medical care.
Learn moreFrequently Asked Questions About Age Management
Is age management the same as anti-aging medicine?
The terms are often used interchangeably. At Bionuu, age management focuses on maintaining health and function as the body changes with age. We evaluate factors that may influence physical and mental well-being and develop individualized recommendations.
What treatments are included in an age management plan?
Depending on your evaluation, your plan may include hormone therapy, NAD+, peptide therapy, IV nutrient therapy, ozone therapy, selected medications, and nutritional or lifestyle recommendations. Not every treatment is appropriate for every patient.
Do I need laboratory testing before starting?
Laboratory testing is an important part of our evaluation. The specific tests recommended depend on your medical history, symptoms, and treatment goals. Follow-up testing may also be necessary to monitor certain treatments.
What is NAD+ therapy?
NAD+ is a naturally occurring coenzyme involved in cellular metabolism and energy production. Intravenous NAD+ is used in some age management programs, although research into its long-term clinical benefits is ongoing.
What does off-label prescribing mean?
Off-label prescribing refers to the use of a prescription medication for a purpose different from its originally approved indication. Physicians may consider off-label treatment when there is an appropriate clinical rationale. The available evidence, potential benefits, risks, and alternatives should be discussed before treatment.
How quickly can I expect results?
The timeline depends on the concerns being addressed, the treatments selected, and individual factors. Some changes may be noticeable within weeks, while others require longer-term management. Not all patients experience improvement, and no specific outcome can be guaranteed.
Can age management stop or reverse aging?
No treatment has been established to stop the aging process. Age management focuses on identifying and addressing factors that may influence health, physical function, and quality of life as people grow older.
Do you see patients from outside Denver?
Yes. We serve patients throughout the greater Denver area, including Centennial, Highlands Ranch, Littleton, Englewood, Greenwood Village, Lone Tree, Parker, and surrounding communities. Phone and video consultations are also available for eligible patients in Colorado and Pennsylvania. In-clinic therapies are performed in person.
Where is Bionuu located?
Bionuu Functional Medicine Denver is located at 6650 S. Vine St, Suite 240, Centennial, CO 80121. Phone: 303-942-0159. Hours: Monday–Friday, 9:00 AM–5:00 PM.
Age Management Services in the Denver Area
Bionuu Functional Medicine Denver provides physician-led age management services for patients throughout the Denver metropolitan area. Our clinic is conveniently located in Centennial, approximately 20 minutes south of downtown Denver. We welcome patients from Denver, Centennial, Highlands Ranch, Littleton, Englewood, Greenwood Village, Cherry Hills, Lone Tree, Parker, Aurora, Lakewood, Castle Rock, and surrounding communities.
Schedule an Age Management Consultation
If you are interested in maintaining your health and function as you age, we invite you to schedule a consultation. We will review your medical history, discuss your goals, and evaluate which approaches may be appropriate for you.
Medical Disclaimer. This page is intended for general educational purposes and does not constitute individualized medical advice. Age management therapies do not stop or reverse aging, and no specific treatment outcome can be guaranteed. Some therapies have limited clinical evidence or are used off-label. All recommendations are made following an appropriate medical evaluation, taking into account the patient's medical history, potential risks, and individual needs. Patients should consult a qualified healthcare professional before beginning any new treatment.